KMID : 0882420070730040428
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Korean Journal of Medicine 2007 Volume.73 No. 4 p.428 ~ p.431
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A case of acute myocardial infarction associated with amphetamine abuse
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Lee Sung-Ho
Lee Kyung-Eun Lee Kwang-Je Kim Sang-Wook Kim Tae-Ho Kim Chee-Jeong Ryu Wang-Seong
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Abstract
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Acute myocardial infarction is a rarely reported complication of amphetamine abuse. We report here on a case of a
39-year-old man who presented with cardiac enzyme patterns, a clinical history and an ECG that were all compatible
with acute ST elevation myocardial infarction. This was probably the result from self administration of intravenous
amphetamine. The initial coronary angiogram (CAG) showed total occlusion of the distal right coronary artery (RCA)
with a large thrombus. Because the RCA was tortuous and removal of thrombus was thought not to be easy, he was
treated with thrombolytic therapy and intravenous heparin followed by oral warfarin. The follow-up CAGs at 2 weeks
and 10 months later showed almost complete resolution of the coronary abnormalities. In this case, the early coronary
angiography was thought to be helpful to determine the relative contribution of thrombus and spasm that were associated
with amphetamine abuse
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KEYWORD
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Myocardial infarction, Amphetamine
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